You have been prescribed this medicine if you have any of the following:
You should consult your doctor if you experience any of the following:
Usually the preparation is well tolerated. During a long-term usage of high doses there can be possible follow side effects:
nausea, vomiting, heartburn, diarrhea.
hyperexcitability of CNS, headache.
formation of urinary, cystine and oxalate concernments.
Skin and subcutaneous tissue: allergic reactions.
It can cause erythrocyte hemolysis in patients with insufficiency of glucose-6-phosphatdehydrogenase of hematocytes.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise take it as soon as you remember and then go back to taking it as you would normally.
Ascozin® increases salicylates (increases a risk of crystalluria), ethynilestradiol,
benzylpenicillin and tetracyclines concentrations in blood, and decreases per oral
contraceptives concentration in blood. It reduces anticoagulation effect of coumarin
derivatives. It improves iron drugs absorption in intestine. It increases general
clearance of ethyl alcohol. Quinolone drugs, calcium chloride, salicylate, corticosteroid
decrease vitamin C reserve when used for a long term. Corticosteroids (cortisone
and prednisolone), which are administered in concrete diseases (arthritis, bronchial
astma etc), also reduce vitamin C and zinc levels.
Concurrent usage of ascorbic acid and deferoxamine enhances tissue toxicity of iron, especially in cardiac muscle that can cause decompensation of blood circulatory system. It can be used only in 2 hours after deferoxamine injection. A long-term administration of high doses in patients, who are treated by disulfiram, inhibits disulfamide-alcohol reaction.
High doses of the preparation decrease efficacy of tricyclic depressants.
nausea, vomiting, intestine spasm, diarrhea; it is possible allergic reaction, kidney dysfunction, blood pressure increase, hyperexcitability of CNS, sleep disturbance.
It is symptomatic.
Tell your doctor immediately if you become pregnant while taking this medication. For safety of any drug during pregnancy or breastfeeding – please consult your doctor.
Store in a dry, protected from light place at a temperature not more than 25° C.
Keep it out of reach of children.
5 mL of syrup contains spissum extract (3:1) of a mixture of herbs:
Anacyclus pyrethrum 10 mg, Cubeba officinalis 10 mg, Piper nigrum 10 mg, Zingiber officinale 10 mg, Curcuma longa 20 mg, Piper longum 30 mg, Clerodendron serratum 40 mg, Viola odorata 50 mg, Juniperus communis 50 mg, Ocimum sanctum 60 mg, Terminalia belerica 100 mg, Solanum xanthocarpum 120 mg, Glycyrrhiza glabra 150 mg, Adhatoda vasica 200 mg; (extractant: water); ammonium chloride 15 mg;
Liquid glucose, Sucrose, Sodium Benzoate (Е 211), Sodium Methyl Paraben (Е 219), Sodium Propyl Paraben (Е 217), Citric acid, monohydrate; Flavour Grape 1400.
Treatment of all types of productive and nonproductive cough caused by upper respiratory tract infections, bronchitis, focal pneumonia, bronchiectasis, bronchial asthma, tuberculosis, prevention of cough due to occupational conditions, smokers cough. It is also recommended for allergic rhinitis, sore throat, laryngitis, pharyngitis, tonsillitis as a component of symptomatic therapy.
Adults and children over 12 years of age are prescribed 10 mL of syrup 4 times per day, children aged 2-12 years – 5 mL 4 times per day, children aged 1-2 years – 2.5 mL 4 times per day.
The course of treatment is determined individually and depends on the course of disease, but it shouldn't exceed 7 days.
Hypokalemia; edema; hypersensitivity reactions including skin rash, hyperemia, itching. .
Kofol® can be simultaneously used with antibiotics and other chemotherapeutical medicinal agents, antipyretics and vitamins.
Pregnancy and lactation:
Since there is no experience of using Kofol ® during pregnancy and lactation, it should not be prescribed in this group of patients.
Kofol® Syrup is administered in children from 1 year of age.
Caution should be exercised when prescribing Kofol® syrup to patients with diabetes mellitus, as it contains glucose.
It should not be used in patients with fructose intolerance, malabsorption of glucose, galactose and / or sucrose-isomaltase.
The clinical symptoms of overdose are:
Nausea, vomiting, loss of appetite, nervous excitement, change of smell of the urine, purple color of the urine, pain in the kidneys, albuminuria, hematuria, increased diuresis, gastrointestinal disturbances, increased heart rate. First aid consists in immediate gastric lavage. In future the therapy is symptomatic.
Ability to influence reaction velocity while driving or operating any other mechanisms.
There are no data on the effect of the preparation Kofol® on driving motor transport or operating potentially dangerous mechanisms, therefore, while taking the preparation you should refrain from the above activities.
Hypersensitivity to the components of the preparation, salicylates, glomerulonephritis, hepatitis, organic heart disease, hypertension, hypokalemia, severe degree of obesity.
Pharmacotherapeutic group. Combined drugs used for cough and catarrhal diseases. Code АТС R05X.
Kofol® is a herbal and mineral preparation active against cough, cold, it facilitates expectoration. Pharmacological effect is provided by the components of the preparation which combine several mechanisms.
Kofol® is a combination of herbal extracts and ammonium chloride for maintaining normal respiratory function. Eases cough and bronchospasm symptoms.
The active substances of the syrup have the following effect:
Adhatoda vasica, Solanum xanthocarpum, Clerodendron serratum, Piper longum help improve sputum expectoration, act as spasmolytic agents.
Glycyrrhiza glabra has emollient effect, reduces irritation.
Viola odorata, Curcuma longa, Cubeba officinalis, Zingiber officinale, Piper nigrum also reduce irritation and have diaphoretic, anti-inflammatory effect.
Terminalia belerica improves expectoration.
Ocimum sanctum is an anti-catarrhal and anti-infectious agent.
Juniperus communis provides expectorant and anti-septic effect.
Anacyclus pyrethrum has a sedative effect.
Ammonium Chloride provides phlegm liquefaction.
General physic-chemical properties:
Viscous reddish-brown fluid with a characteristic odor and sweet taste. During storage, precipitation is possible.
Store at the temperature not more than 25°С; keep out of reach of children.
100 in a bottle; 1 bottle in a carton.
Conditions of supply: